Comprehensive list of Tamil movies released in 2006. Click on movie names for more details.
| Movie Name | Director | Cast |
|---|---|---|
| E | S.P. Jananathan | Jiiva, Nayantara, Pasupathy |
| Pudhupettai | Selvaraghavan | Dhanush, Sneha, Sonia Agarwal, Vijay Sethupathi |
| Paramasivan | P. Vasu | Ajith Kumar, Laila, Jayaram |
| Saravana | K. S. Ravikumar | Silambarasan, Jyothika, Prakash Raj |
| Aadhi | Ramana | Vijay, Trisha |
| Pasa Kiligal | Amirtham | Prabhu, Murali, Vineeth, Navya Nair, Malavika, Roja |
| Dishyum | Sasi | Jiiva, Sandhya |
| Idhaya Thirudan | Saran | Jayam Ravi, Kamna Jethmalani |
| Amirtham | K. Kannan | Navya Nair, Ganesh |
| Chithiram Pesuthadi | Mysskin | Narain, Bhavana |
| June R | Revathy S. Varma | Jyothika, Kushboo, Saritha |
| Kodambakkam | Jagan | Nandha, Diya, Tejashree |
| Kalabha Kadhalan | Igore | Arya, Renuka Menon, Akshaya |
| Kalvanin Kadhali | Thamilvaanan | S. J. Surya, Nayantara |
| Madarasi | Arjun | Arjun, Vedhika |
| Nagareega Komali | Ramji S.Balan | Jai Sakthi, Neethashree |
| Thambi | Seeman | R. Madhavan, Pooja Umashankar |
| Kovai Brothers | Sakthi Chidambaram | Sathyaraj, Sibiraj, Namitha, Uma |
| Chithiram Pesuthadi(Re-Release) | Mysskin | Narain, Bhavana |
| Oru Kaadhal Seiveer | Bhargawan | Santhosh, Archana Galrani, Krishan |
| Sudesi | A. Y. Jeppy | Vijayakanth, Ashima Bhalla |
| Mercury Pookkal | S. S. Stanley | Srikanth, Meera Jasmine |
| Pattiyal | Vishnuvardhan | Arya, Bharath, Pooja Umashankar, Padmapriya |
| Theenda Theenda | A. P. Muhan | Shivhasan, Preethi Varma |
| Azhagai Irukkirai Bayamai Irukkirathu | Vijay Milton | Bharath, Mallika Kapoor |
| Pachchak Kuthira | R. Parthiban | R. Parthiban, Namitha |
| Thirupathi | Perarasu | Ajith Kumar, Sadha |
| Thiruttu Payale | Susi Ganesan | Jeevan, Sonia Agarwal, Malavika, Abbas |
| Suyetchai MLA | Guru Dhanapal | Sathyaraj, Goundamani, Mantra, Abitha |
| Kokki | Prabu Solomon | Karan, Pooja Gandhi |
| Madhu | K. Thennarasu | Jithan Ramesh, Priyamani |
| Jerry | S. B. Khanthan | Jithan Ramesh, Shruthi Raj, Mumtaj, Meera Vasudevan |
| Thalai Nagaram | Suraj | Sundar C., Jyothirmayi, Vadivelu |
| Kalinga | Ram Prabha | Bala, Nandhana |
| Vanjagan | A. M. Bhaskar | Pradap, Chandrahasan, Sujibala, Suman |
| Don Seera | K. S. Saravanan | Ranjith, Sujibala |
| Parijatham | K. Bhagyaraj | Prithviraj, Saranya Bhagyaraj |
| Kaivantha Kalai | Pandiarajan | Prithvi, Shruthi, Pandiarajan, Malavika |
| Naalai | Udhayabanu Maheswaran | Richard Rishi, Natarajan Subramaniam, Madhumitha |
| Aacharya | Ravi | Vignesh, Divya, Nassar |
| Kusthi | Raj Kapoor | Prabhu, Karthik Muthuraman, Manya, Flora |
| Uyir | Samy | Srikanth, Sangeetha, Samvrutha Sunil |
| Thullura Vayasu | Gopal | Raghav, Deepika |
| Imsai Arasan 23m Pulikesi | Chimbu Deven | Vadivelu, Monika, Tejashree |
| Thodamale | V. Rajendra Kumar | Narain, Uma |
| Thoothukudi | Sanjay Ram | Harikumar, Karthika |
| Yuga | 'Yaar' Kannan | Richard Rishi, Swarnamalya, Manikandan, Nassar, Santhoshi |
| Unakkum Enakkum | M. Raja | Jayam Ravi, Trisha, Prabhu, K. Bhagyaraj, Richa Pallod |
| Kadhale En Kadhale | P. C. Sekar | Naveen, Roma Asrani, Shrutha |
| Thimiru | Tarun Gopi | Vishal, Reema Sen, Sriya Reddy |
| Kurukshetram | Jaya Bharathi | Sathyaraj, Roja |
| Nee Venunda Chellam | L. Venkatesan | Jithan Ramesh, Gajala, Namitha |
| Vettaiyaadu Vilaiyaadu | Gautham Menon | Kamal Haasan, Jyothika, Kamalinee Mukherjee, Prakash Raj |
| 16 Naatkal | Ravi Srinivas | R. S. K. G, Ananthy, Ganaa Ulakanathan |
| Em Magan | Thirumurugan | Bharath, Gopika, Nassar, Saranya Ponvannan, Vadivelu |
| Jambhavan | Nandhakumar | Prashanth, Nila, Meghna Naidu |
| Sillunu Oru Kaadhal | N. Krishna | Suriya, Jyothika, Bhumika Chawla |
| Perarasu | Udhayan | Vijayakanth, Debina Bonnerjee |
| Manathodu Mazhaikalam | Arputhan | Shaam, Samiksha, Nithya Das, Jayasurya |
| Kedi | Jyothi Krishna | Ravi Krishna, Ileana D'Cruz, Tamannaah |
| Ilavattam | A. R. Raviraja | Navdeep, Sheela |
| Maranthen Meimaranthen | Sivaram | Yoha, Poornitha |
| Dharmapuri | Perarasu | Vijayakanth, Lakshmi Rai |
| Varalaru | K. S. Ravikumar | Ajith Kumar, Asin, Kanika |
| Thalaimagan | Sarath Kumar | Sarath Kumar, Nayantara |
| Vallavan | Silambarasan | Silambarasan, Nayantara, Reema Sen, Sandhya |
| Vattaram | Saran | Arya, Kirat Bhattal, Napoleon |
| Kizhakku Kadalkarai Salai | S. S. Stanley | Srikanth, Bhavana |
| Vathiyar | A. Venkatesh | Arjun, Mallika Kapoor |
| Aavani Thingal | Hari Krishna | Srikumar, Madhusa, Tejini |
| Prathi Gnayiru 9.30 to 10.00 | M. Anbu | Ramesh, Poornitha, Karunas |
| Rendu | Sundar C. | R. Madhavan, Reema Sen, Anushka Shetty |
| Sivappathigaram | Karu Pazhaniappan | Vishal, Mamta Mohandas, Raghuvaran |
| Iruvar Mattum | Dwaraki Raghavan | Abhinay, Sunitha Varma |
| Idhu Kadhal Varum Paruvam | Kasthuri Raja | Harish Kumar, Kiran, Lakshmi Priya, Preeti Buttali |
| Nenjil Jil Jil | Selva | Navdeep, Aparna Pillai |
| Chennai Kadhal | Vikraman | Bharath, Genelia D'Souza |
| Aadu Puli Aatam | Sanjay Ram | Mani Prakash, Vennila, Rekha Sri |
| Ganapathy Vanthachi | P. C. Guna | Udhay, Rajesh, Pandu, Charle |
| Nenjirukkum Varai | S. A. Chandrasekhar | Narain, Poonam Kaur |
| Thiruvilaiyaadal Aarambam | Boopathy Pandian | Dhanush, Shriya Saran, Prakash Raj |
| Veyil | Vasanthabalan | Pasupathy, Bharath, Bhavana, Sriya Reddy, Priyanka Nair |
| Azhagiya Asura | Nagu | Yogi, Regina, Nandita |
| Ilakannam | Chandraseyan | Ram, Uma |
| Poi | K. Balachander | Uday Kiran, Vimala Raman, Geethu Mohandas |
| Thirudi | K. Shankar | Murli, Dhanya |
| Thagapansamy | Shiva Shanmugam | Prashanth, Pooja Umashankar, Namitha |
| Adaikalam | Bhuvanaraja | Prashanth, Uma, Thyagarajan |
| Kaasu | Gowri Manohar | Rahman, Sangeetha, Rajashri |